AI Commercial Excellence Programme

Prompting for Impact

The Chugai Marketing AI Foundation. A practical playbook for getting elite-level work out of Claude Enterprise, grounded in the 4Cs framework from PACE training.

For Helen Millar · 13 May 2026 · Foundation Edition v1.0

Why this exists

The gap between average and elite AI users is huge. The skill that closes it is prompting.

Most teams treat AI like a search engine. Elite users treat it like a junior analyst. The output gap between those two approaches is bigger than the gap between Claude Opus and ChatGPT 3.5. The skill that creates that gap is not paying for the better model. It is prompting.

01

A framework

The 4Cs — which you already know from PACE — applied as your prompting spine.

02

Three habits

That compound across every chat from today onwards. Save once, use forever.

03

Ten prompts

A starter promptbook calibrated for Chugai Oncology Marketing. Copy, adapt, save.

Your prompting spine

The 4Cs framework

From Chugai PACE training. Every prompt scored against four questions. The weakest C is where the next correction round will come from.

C1

Clear

What exactly do you want, in what shape?

  • Output format
  • Length and structure
  • Deliverable type
C2

Context

What does Claude need to know about the situation?

  • Role and audience
  • Business background
  • Prior work
C3

Constraints

What must (and must not) be true about the output?

  • Compliance lens
  • Must-haves and must-not-haves
  • Standing rules
C4

Check

How will you verify the output is right?

  • Sources cited or flagged
  • Calculations interrogated
  • Sceptical second look
Try it now: take any prompt you have sent in the last week. Score each C from 1 to 5. The weakest C is where the next correction round will come from. Use the scorer below to try it on a real example.

The single biggest unlock

Build your reusable context block

Stop typing the same context into every new chat. Save it once inside a Claude Enterprise Project, in the Custom Instructions field. Every chat you start inside that Project inherits it automatically. Six messages of correction become one good first draft.

Your context block

        

Paste this into Claude Enterprise → Projects → Custom Instructions. Save once. Apply forever.

Before you hit send

The 30-second pre-send check

Run this seven-point check before any prompt that matters. If all seven are answered in the prompt, you have already won most of the iteration rounds before they start.

Tap each item as you confirm it. Print the pocket card (below) and pin it next to your monitor for the first two weeks. After that it is reflexive.

Section II

The Advanced Moves

Eight techniques to compound your output quality. Pick two, build the habit, add more.

1

The Two-Model Critique

Check

Critique drafts in a NEW chat, never the same one. Fresh context means no anchoring. The same chat is committed to the framing it just produced. A new chat is brutal.

See the template
You are a sceptical ExCo member. You have
five minutes before the meeting. Find three
weaknesses in this paper, and the one question
that would derail the recommendation in the
room.
2

The Output Template

Clear · Constraints

Show the format, do not describe it. Claude follows literal templates almost perfectly. It interprets prose descriptions loosely.

See the template
Output exactly as below. No preamble.
No closing remarks.

TITLE (max 8 words):
BLUF (max 30 words):
KEY POINTS (3, one sentence each):
RISKS (max 3, flagged commercial / ABPI / comp law):
DECISION NEEDED:
3

The Quote-the-Paragraph Check

Check

The hallucination killer. Generic "where did this come from?" produces plausible-sounding citations. Force it to quote, verbatim.

See the template
For each claim above, quote the exact sentence
from the source document. If you cannot quote
it, mark the claim as inferred.
4

Negative Prompting

Constraints

Tell it what NOT to do. When you ask Claude for an ExCo paper, the first draft typically comes back padded with hedging phrases — "it is worth noting that", "while it is important to recognise", "this is not without its challenges". A short negative-prompt block stops Claude producing them in the first place. You save five minutes per paper.

See the template
Constraints:
- No marketing buzzwords
- No "consult your legal team" caveats
- No invented statistics
- No qualifying phrases like "it is worth noting"
- No bullet points longer than one line
- No closing sentence that summarises the document
5

The Worst-Headline Test

Check · Pharma

Pharma-specific pre-mortem. Internal documents leak. ExCo decks get forwarded. Run this on more than just press materials.

See the template
If this content leaked to PMLive or Pharma
Letter tomorrow, what is the worst possible
headline a journalist could write? Rewrite to
eliminate that risk.
6

The Pre-Mortem

Check

Imagine the decision failed in twelve months. What would the post-mortem say? Run this on the strong cases too, not just the weak ones.

See the template
Imagine this recommendation was approved,
then failed twelve months later. What is the
single most likely reason it failed? What are
we missing now that we will regret then?
7

Few-Shot by Screenshot

Clear

One image is worth a thousand instructions. For format-sensitive output, paste a screenshot of "here is what good looks like". Eliminates iteration rounds on layout.

See the template
Here is what good looks like for this slide
format. Match this layout, this density of
text, and this style of heading.
[paste screenshot]
8

The Ask-Me-Questions Preamble

Context

For complex business cases. Reserve for prompts where assumption errors will be expensive. Catches the silent assumptions before the first draft.

See the template
Before you start, ask me up to five questions
where my answer would materially change your
output. Wait for my answers before drafting.

Section III

Pharma-Specific Hygiene

The constraints AI doesn't know by default. Non-negotiable for any output that could face external eyes.

Data classification before paste

Treat the chat window like an email you might forward by mistake. Before pasting, check the source against Chugai's data handling policy.

Do not paste:

  • Identifiable HCP data
  • Patient-level data
  • Anything classified Chugai Confidential without confirming policy
  • Partner commercial terms (Helsinn or otherwise) without confirming sharing rights
  • Pre-publication study data
  • Anything under embargo

When in doubt: redact first, prompt second.

The triple compliance pass

Three passes, three clean contexts. Catches what a single chat misses.

  1. Draft chat — produce the content.
  2. New chat (clean context) — "Review this draft line by line against the current ABPI Code of Practice. Flag every potential breach. Cite the clause."
  3. New chat (clean context) — "Act as a UK CMA lawyer specialising in pharmaceutical competition. Flag every competition law risk, particularly comparative claims."

Standing pharma constraints

Build these into your context block so they apply automatically:

  • Disease-area claims must be on-label
  • Comparative claims must be substantiated by referenced data
  • Off-label discussion is flagged, not produced
  • Patient-facing content respects health literacy norms
  • HCP-facing content respects the Code distinction between promotional and non-promotional material

Section IV

The Starter Promptbook

Ten prompts you can adapt this afternoon. Calibrated for Chugai Oncology Marketing. Click to expand, copy to clipboard, save to your Project.

Interactive tool

The 4Cs Prompt Scorer

Paste a prompt below and score it against the 4Cs framework. The scorer is heuristic, not authoritative — useful as a teaching tool and a sanity check. Trust your own judgement on the borderline calls.

Section V

The Six-Week Rollout

Embedding the practice across the team. This is not training — it is practice. Each week has one focus and one outcome.

  1. Week 1
    Mindset and the 4Cs
    Every team member can score a prompt against the 4Cs.
  2. Week 2
    The context block
    Every team member has a personal context block saved in a Project.
  3. Week 3
    Output templates + 30-second check
    Three standard output templates adopted across the team.
  4. Week 4
    Compliance hygiene
    Every team member has used the triple compliance pass at least once on a real document.
  5. Week 5
    The Two-Model Critique
    Every team member has critiqued one of their own drafts in a new chat.
  6. Week 6
    Promptbook and team review
    Each team member contributes three prompts to the team promptbook.

Three maturity tiers

Beginner
  • One-line prompts
  • Generic outputs
  • Accepts first draft
Capable
  • Front-loads context
  • Sets standing rules
  • Sometimes challenges output
Expert
  • Uses Projects deliberately
  • Critiques drafts in new chats
  • Coaches others

Aim: median team member reaches Capable by week 6. Expert by month 6.

Print and pin

The Pocket Reference Card

Print one per attendee for the kick-off session. Pin one next to your monitor for the first two weeks. After that the habits are reflexive.

Prompting for Impact

Pocket reference card

The 4Cs

ClearWhat do I want, in what shape?
ContextWhat does Claude need to know?
ConstraintsWhat must (and must not) be true?
CheckHow will I verify the output?

The 30-second pre-send check

  1. Audience named?
  2. Format and length specified?
  3. Persona assigned?
  4. Must-haves and must-not-haves listed?
  5. Compliance lens flagged?
  6. Uncertainty handling stated?
  7. Disagreement handling stated?

The Master Rules

  1. Front-load — audience, format, length, persona, constraints.
  2. One brief, not six messages.
  3. Challenge the maths, always.
  4. Quote or flag — no claim without a verifiable source.
  5. Two contexts beat one — critique in a new chat.
  6. Save what works — promptbook discipline compounds.
  7. You are accountable — never copy-paste raw output.

The three habits that matter most

  1. Save your context block in a Project.
  2. Run the 30-second check before send.
  3. Critique drafts in a new chat, not the same one.
Download print-ready PDF

Take it with you

Downloads

The full Foundation Kit. All formats, ready to share with your team and stakeholders.

📦

The complete package

Everything below in a single zip file. 14 MB. Self-contained — share via email or OneDrive.

ZIP · 14 MB
Start Here

Welcome note and orientation. Read first.

PDF
The Foundation Toolkit

14 sections plus appendices. The full reference manual.

Training Deck Outline

40 slides, layout · content · speaker notes · visual direction.

Pocket Reference Card

Print-ready A5 card. Pin next to your monitor.

PDF
Deck Hero Images

Six editorial 1792×1024 PNGs for the training deck.

Six weeks from today.

We come back. We compare promptbooks. We see what changed.